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电话：+86-755-86967710
邮箱：webmaster@szbl.ac.cn
Jianzhi Zeng, Ph.D./
Institute/Center
Institute of Molecular Physiology
Email
zengjz@szbl.ac.cn
Research Direction
Molecular Biology,Neuroscience,Immunology
Timeline
Areas
Results
Honors
Media
Recruitment
Papers
Timeline
2024 – Present
Shenzhen Bay Laboratory
Shenzhen Bay Fellow
2022 – 2024
Shenzhen Bay Laboratory
Postdoc
2021 – 2022
CoStone Capital
Analyst
2015 – 2021
Peking-Tsinghua Center for Life Sciences
PhD
2011 – 2015
Hunan University
Bachelor
Research Areas
Jianzhi Zeng's research group is dedicated to developing neuroimaging techniques to explore the molecular dynamics of critical signals in both pathological and physiological processes.
1. Development of fluorescent protein-based indicators.
2. Investigation of the etiology and intervention of neuroinflammation.
3. Exploration of the circuit and molecular mechanisms of learning and memory.
Highlights
Development of fluorescent dopamine sensor. It enables the detection of dopamine molecular dynamics in olfactory perception, fear behavior, learning and memory, and social behavior in live fruit flies, zebrafish, and mice (Cell, 2018). This work was selected as one of the 'Top Ten Scientific Advances in Chinese Life Sciences in 2018' and was featured in a popular science report by thePeople's Daily.
Focusing on the effective time interval of 'bell and food' in Pavlovian learning, we revealed the molecular and neural circuit mechanisms by which serotonin regulates the time window for learning and memory (Neuron, 2023). This research was featured in a popular science report by thePeople's Daily.
Honors
2024 Excellent Postdoctoral Fellow in Shenzhen City
2023 Junior Talent Program, China Association for Science and Technology
2023 Third Prize of the National Young Researcher in Physiology, C. C. Chang Foundation, Chinese Physiological Society
2023 The Hsiang-Tung Chang Outstanding Graduate Thesis Award in Neuroscience, Chinese Neuroscience Society
2021 Ray Wu Prize, Ray Wu Foundation
Media
Recruitment
Papers
1.Zeng, J.*#, Li, X.*, Zhangren, Z., ... & Li, Y.# (2023). Local 5-HT signal bi-directionally modulates the coincident time window of associative learning.Neuron.(*co-first author; #co-corresponding author)
2.Zeng, J., Sun, F., Wan, J., Feng, J. & Li, Y.# (2019). New optical methods for detecting monoamine neuromodulators.Current Opinion in Biomedical Engineering.
3. Sun, F.*,Zeng, J.*, Jing, M.*, Zhou, J., Feng, J., Owen, S., ... & Li, Y.# (2018). A genetically-encoded fluorescent sensor enables rapid and specific detection of dopamine in flies, fish, and mice.Cell.(*co-first author)
Full publication list:
https://scholar.google.com.hk/citations?user=c4lK_QoAAAAJ&hl=zh-CN
Contact
Address: Gaoke Innovation Center,Guangming District, Shenzhen
Phone: +86-755-86967710
Email: webmaster@szbl.ac.cn
Postal Code: 518132
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