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地址：深圳市光明区光侨路高科创新中心
电话：+86-755-86967710
邮箱：webmaster@szbl.ac.cn
电话：+86-755-86967710
邮箱：webmaster@szbl.ac.cn
Lang Rao, Ph.D./
Institute/Center
Institute of Chemical Biology
Email
lrao(at)szbl.ac.cn
Research Direction
Chemistry,Pharmacology,Biomedical Engineering
Homepage Link
Timeline
Areas
Results
Honors
Media
Recruitment
Papers
Timeline
2020 - Present
Shenzhen Bay Laboratory
Junior Principal Investigator
2019 - 2020
National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health (NIH)
Postdoc
2018 - 2019
Simmons Comprehensive Cancer Center, UT Southwestern Medical Center
Postdoc
2013 - 2018
Wuhan University
PhD
2009 - 2013
Wuhan University
Bachelor
Research Areas
My research aims to create cutting-edge biomimetic nanotechnology and exploit them to study and solve complex biological problems that are associated with human diseases. One major research goal is to overcome the various therapeutic barriers in the treatment of cancer and viral infection. I also seek to understand the fundamental sciences at the interface of nanomedicine and biology. Overall, my research program covers a broad scope of multidisciplinary areas including chemistry, materials science, nanotechnology, biotechnology and medicine.
Honors
2022 Excellent Youth Fund, National Science Foundation of China
2022 May-First Labor Medal, Shenzhen
2021 Overseas High-Caliber Personnel, Shenzhen
2017 Future Scientist Award, Biomaterials
Media
Recruitment
Papers
1. D. Wu*, K. Yang,L. Rao*, X. Chen*, & G. Yu*. Metal-free bioorthogonal click chemistry in cancer theranostics.Chem. Soc. Rev., 2022, 51, 1336-1376.
2. Q.-F. Meng, Y. Zhao, C. Dong, Y. Pan, L. Liu, J. Lai, Z. Liu, G.-T. Yu*, X. Chen*, &L. Rao*. Genetically Programmable Fusion Cellular Vesicles for Cancer Immunotherapy.Angew. Chem. Int. Ed., 2021, 60, 26320-26326.
3. Q.-F. Meng, R. Tian, H. Long, X. Wu, J. Lai, O. Zharkova, J.-W. Wang*, X. Chen*, &L. Rao*. Capturing Cytokines with Advanced Materials: A Potential Strategy to Tackle COVID-19 Cytokine Storm.Adv. Mater., 2021, 33, 2100012.
4.L. Rao, S. Xia, W. Xu, R. Tian, G. Yu, C. Gu, P. Pan, Q.-F. Meng, X. Cai, D. Qu, L. Lu*, Y. Xie*, S. Jiang*, and X. Chen*. Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines.Proc. Natl. Acad. Sci. USA, 2020, 117, 202014352. (Featured as Cover; Highlighted by The Scientist; Chemistry Views; Inverse; Infosurhoy; Scitech Daily).
5.L. Rao, L. Wu, Z. Liu, R. Tian, G. Yu, Z. Zhou, K. Yang, H.-G. Xiong, A. Zhang, G.-T. Yu, W. Sun, H. Xu, J. Guo, A. Li, H. Chen*, Z.-J. Sun*, Y.-X. Fu*, & X. Chen*. Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis.Nat. Commun., 2020, 11, 4909.
6.L. Rao*, Y. Yuan, X. Shen, G. Yu & X. Chen*. Designing nanotheranostics with machine learning.Nat. Nanotechnol., 2024, in press. DOI: 10.1038/s41565-024-01753-8.
7. J. Wu, H. Lu, X. Xu,L. Rao*, & Y. Ge*. Engineered Cellular Vesicles Displaying Glycosylated Nanobodies for Cancer Immunotherapy.Angew. Chem. Int. Ed, 2024, 63, e202404889.
8. Q. Meng, W. Tai, M. Tian, X. Zhuang, Y. Pan, J. Lai, Y. Xu, Z. Xu, M. Li, G. Zhao, G. Yu, G. Yu, R. Chen, N. Jin, X. Li*, G. Cheng*, X. Chen*, &L. Rao*. Inhalation delivery of dexamethasone with iSEND nanoparticles attenuates the COVID-19 cytokine storm in mice and non-human primates.Sci. Adv., 2023, 9, eadg3277.
Contact
Address: Gaoke Innovation Center,Guangming District, Shenzhen
Phone: +86-755-86967710
Email: webmaster@szbl.ac.cn
Postal Code: 518132
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