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地址：深圳市光明区光侨路高科创新中心
电话：+86-755-86967710
邮箱：webmaster@szbl.ac.cn
电话：+86-755-86967710
邮箱：webmaster@szbl.ac.cn
Yuzong Chen, Ph.D./
Institute/Center
Institute of Biomedical Health Technology and Engineering
Email
chenyuzong(at)sz.tsinghua.edu.cn
Research Direction
Computational Biology,Pharmacology
Timeline
Areas
Results
Honors
Media
Recruitment
Papers
Timeline
2021 - Present
Shenzhen Bay Laboratory
Senior Principal Investigator
2013 - Present
Tsinghua University Shenzhen International Graduate School
Professor
2007-2021
Department of Pharmacy, National University of Singapore
Professor
2006
Department of Pharmacy, National University of Singapore
Associate Professor
2004 - 2005
National University of Singapore
Head of Dept of Computational Science
1997 - 2005
Department of Computational Science, National University of Singapore
Assistant Professor/Associate Professor
1997
Ionis Pharmaceuticals
Scientist
1996 - 1997
University of Toledo
Visiting Assistant Professor
1989 - 1996
Purdue University
Postdoc
1985–1989
University of Manchester, UK
PhD
1982–1985
Institute of Theoretical Physics, Chinese Academy of Sciences
MSc
Research Areas
1. AI in biomedical applications
2. Bioinformatics
3. Computer aided drug design
4. Science and arts (protein art, protein music)
Highlights
- Invented inverse docking method for target discovery
- Developed the popular therapeutic target database TTD
- One of the pioneers in machine learning drug discovery and biological research
- Successfully predicted clinical success of drug targets
- Discovered clustered patterns of nature-derived drugs
Research indicators: H-Index 49 (SCI), 52 (Scopus), Citations: 8940 (SCI), 9761 (Scopus)
Honors
Outstanding Scientist Award 2007, Science Faculty, National University of Singapore
Media
Recruitment
Papers
1. Shen, Wanxiang; Zeng, Xian; Zhu, Feng; Wang, Yali; Qin, Chu; Tan, Ying; Jiang, Yuyang*;Chen, Yuzong*, Out-of-the-box deep learning prediction of pharmaceutical properties by broadly learned knowledge-based molecular representations.Nat. Mach. Intell.,2021,3(4), 334-343.
2. Li, Yinghong; Li, Xiaoxu; Hong, Jiajun; Wang, Yunxia; Fu, Jianbo; Yang, Hong; Yu, Chunyan; Li, Fengcheng; Hu, Jie; Xue, Weiwei; Jiang, Yuyang; Chen, Yuzong*; Zhu, Feng*, Clinical trials, progression-speed differentiating features and swiftness rule of the innovative targets of first-in-class drugs.Briefings in Bioinformatics,2020,21(2), 649-662.
3. Zeng, Xian; Zhang, Peng; Wang, Yali; Qin, Chu; Chen, Shangying; He, Weidong; Tao, Lin; Tan, Ying; Gao, Dan; Wang, Bohua; Chen, Zhe; Chen, Weiping*; Jiang, Yuyang*;Chen, Yuzong*, CMAUP: a database of collective molecular activities of useful plants.Nucleic Acids Research,2019,47(D1), D1118-D1127.
4. Feng Zhu, Xiaoxu Li, Shengyong Yang,Yuzong Chen*. Clinical Success of Drug Targets Prospectively Predicted by In Silico Study.Trends Pharmacol Sci39(3):229-231. (2018)
5. Zeng, Xian; Zhang, Peng; He, Weidong; Qin, Chu; Chen, Shangying; Tao, Lin; Wang, Yali; Tan, Ying; Gao, Dan; Wang, Bohua; Chen, Zhe; Chen, Weiping*; Jiang, Yuyang*;Chen, Yuzong*, NPASS: natural product activity and species source database for natural product research, discovery and tool development.Nucleic Acids Research,2018,46(D1), D1217-D1222.
Contact
Address: Gaoke Innovation Center,Guangming District, Shenzhen
Phone: +86-755-86967710
Email: webmaster@szbl.ac.cn
Postal Code: 518132
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