ZHOU Chuan's group from the Institute of Molecular Physiology, SZBL, has recently published their study on eLife. Titled “A neuropeptide regulates fighting behavior in Drosophila melanogaster”, the study revealed that a neuropeptide Drosulfakinin (Dsk) modulates aggression in Drosophila melanogaster by functioning downstream of a subset of P1 neurons (P1a-splitGAL4) to control fighting behavior. Conditional overexpression of Dsk promotes social dominance, suggesting a positive correlation between Dsk signaling and winning effects. The mammalian ortholog Cholecystokinin (CCK) has already been investigated in previous studies, showing implication with mammal aggression. Therefore the group’s work suggests a conserved neuromodulatory system for the modulation of aggressive behavior. To find out more about the study, please access: https://elifesciences.org/articles/54229 DOI：http://10.7554/eLife.54229